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Chemical deuteration instrument laboratory
  • biomedical image

    Voucher scheme for accelerating biomedical research

     

    To encourage access to a diverse range of NCRIS supported Australian translational medical research capabilities, Therapeutic Innovation Australia (TIA) has developed the Pipeline Accelerator, a competitive voucher-style scheme that can subsidise the cost of access to a full range of advanced capabilities. In the Pipeline Accelerator 2024-2025 Round 1, TIA is partnering with Phenomics Australia and ANSTO’s National Deuteration Facility (NDF) to expand the list of translation expertise necessary for the discovery and translation of medical research.

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  • calculation of deuteration from MS

    DGet! An open source deuteration calculator for mass spectrometry data

     

    Alexander Angeloski from the National Deuteration Facility and Thomas Lockwood from the University of Technology Sydney have developed a new software tool to enable the routine determination of deuterium content in deuterated molecules using mass spectrometry data.

    DGet! is the first readily available application to determine the deuterium content of small molecules using mass spectra. DGet! is freely available at https://dget.app.

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  • book with sticky tabs

    2024 NDF Product Catalogue released

     

    The 2024 NDF Product Catalogue has been released and is available to download.

  • blood cholesterol

    Major study identifies a potential drug target for lowering cholesterol

     

    ANSTO has contributed to a major study identifying a potential drug target for lowering blood cholesterol that has been published in the prestigious journal Science.

    The international study was enabled by two of Australia’s national research infrastructure facilities, the National Deuteration Facility and Microscopy Australia, both funded by NCRIS.

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  • Silicon surface

    Brothers produce excellent scientific results with improvements to silicon

     

    In a rare collaboration, two scientists, who are brothers working in unrelated disciplines, combined complementary expertise to tackle a chemical problem relating to the use of silicon in electronic devices.

    Leader of the National Deuteration Facility, Dr Tamim Darwish, suggested to his brother, Dr Nadim Darwish, a Senior Lecturer with expertise in molecular electronics at Curtin University, that deuterating silicon might improve its properties.

    This facility at ANSTO is a world leader in deuteration for research applications, and they specialise in providing bespoke deuterated molecules and labelling techniques.

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  • scientific instrument

    ANSTO welcomes federal funding announcement to support research infrastructure and expertise

     

    ANSTO’s National Deuteration Facility (NDF) is excited to announce it has been granted $2.8 million in National Collaborative Research Infrastructure Strategy (NCRIS) 2023 phase 2 funding from the Australian Government for expansion of existing capabilities and development of new capabilities.

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  • scientific plasticware

    Successful ARC Discovery Project 2024

     

    NDF researcher Dr Anthony Duff is a partner investigator on a recently awarded 2024 ARC Discovery Project grant valued at $624,710 entitled "The geometry of genome access: lessons from HIV".

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  • Cell membrane

    Deuterated squalene and sterols from modified yeast

     

    The National Deuteration Facility at ANSTO continues to support biomedical research on COVID-19 by providing bespoke deuterated lipids for studies of the structure of the virus and its complex molecular interactions.

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  • Open book

    NDF staff co-author book chapter on deuteration for biological small angle neutron scattering

     

    Staff from the National Deuteration Facility have co-authored a book chapter featured in “Methods in Enzymology; Small Angle Scattering Part A: Methods for Structural Investigation”.

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  • Person receiving a vaccination

    Deuteration continues to be an important characterisation tool in understanding COVID infectivity and severity

     

    The National Deuteration Facility at ANSTO continues to support biomedical research on COVID-19 by providing bespoke deuterated lipids for studies of the structure of the virus and its complex molecular interactions.

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Acknowledgements

The National Deuteration Facility is partly supported by the National Collaborative Research Infrastructure Strategy – an initiative of the Australian Government.

NCRIS version 2